منابع مشابه
Neurotoxicity of immunosuppressive therapies in organ transplantation.
ABSTRACT Immunosuppressive agents have revolutionized clinical transplantation medicine, allowing the avoidance of immune system attack on the transplanted graft. Nevertheless, the use of medications such as cyclosporine, tacrolimus and others also brought the side effects of these drugs. Early identification of drug-induced neurotoxicity in transplanted patients and of its specific causes is i...
متن کاملImmunosuppressive drugs and fertility
Immunosuppressive drugs are used in the treatment of inflammatory and autoimmune diseases, as well as in transplantation. Frequently prescribed in young people, these treatments may have deleterious effects on fertility, pregnancy outcomes and the unborn child. This review aims to summarize the main gonadal side effects of immunosuppressants, to detail the effects on fertility and pregnancy of ...
متن کاملOral immunosuppressive drugs.
The last few decades have witnessed remarkable achievements in the development of immunosuppressive drugs, made possible by significant advances in molecular immunology and improved understanding of the mechanisms by which cells communicate. The identification of the relevant cells involved in a pathological process is the key to understanding effective immunosuppressive strategies. For example...
متن کاملPharmacodynamic monitoring of immunosuppressive drugs.
Pharmacodynamic (PD) monitoring measures the biological response to a drug, which alone--or coupled with pharmacokinetics--provides a novel method for optimization of drug dosing. PD monitoring has been investigated by us and other investigators primarily for four immunosuppressive drugs: cyclosporine (CsA), azathioprine (AZA), mycophenolate mofetil (MMF), and rapamycin (RAPA). PD monitoring of...
متن کاملSymposium on immunosuppressive drugs. Attributes of clinically used immunosuppressive drugs: possible future uses of antilymphoid sera.
interest by providing: a) a brief summary of accomplishmethods of donor-recipient matching were not available, ments which have already been possible with the admitexcept for the assurance of compatible blood types. The tedly imperfect immunosuppressive regimens now in use; results, therefore, were obtained with relatively random b) a critique of the drugs or drug combinations currently donor s...
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ژورنال
عنوان ژورنال: Liver Transplantation
سال: 2001
ISSN: 1527-6465
DOI: 10.1053/jlts.2001.27475